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Vitamin D - Ergocalciferol ...
...organic
vitamin D within the body.
Vitamin D has many nutrients that are required alongside for optimum utilisation. These include magnesium, Vitamin A, calcium,
Vitamin C, phosphorus, Vitamin F and choline.
If you are taking a calcium supplement to support the bones, you should always
ensure that it also contains Vitamin D as well.
Typically, Vitamin D is naturally synthesized from 7-dehydrocholesterol by UV
exposure to skin. However, with an increase
of people living in cities and being indoors more, many are not getting adequate sunlight,
preventing optimal levels of vitamin D within their bodies.
Once Vitamin D is either synthesized in the skin or ingested, it is transformed
into 25-hydroxycholecalciferol (25-hydroxy vitamin D3) in the liver. Further synthesis is necessary for biologic
activation of vitamin D. This final synthetic
step occurs in the kidney with the formation of 1,25-dihydroxycholecalciferol
(1,25-dihydroxy vitamin D3). This step is the
most tightly regulated point of the biologic activation of vitamin D.
The biological form of Vitamin D effects numerous cell types, although all effects
have not yet been determined.
Metabolically Active Vitamin D
However, metabolically active vitamin D dramatically facilitates intestinal
absorption of calcium plus magnesium and phosphate ions to a lesser degree.
In the kidneys vitamin D promotes re-absorption of calcium. Plus, according to different research vitamin D
promotes differentiation of osteoclasts and vitamin D also positively effects bone tissue.
Vitamin D induces the production of osteocalcin which binds hydroxyapatite –
the key component of bone and dentin.
Studies show that vitamin D deficiency correlates with reduced bone mass density and a consequent increase in the risk of hip
fractures. These findings were validated in
humans by a clinical study showing that calcitriol (1,25-dihydroxy vitamin D3)
administration successfully increased bone mass at the femoral neck in postmenopausal
women.
Furthermore, it seems that vitamin D may have similar effects on children and
adolescents.
Other factors such as synthetic sunscreens which block UV radiation and
geographical locations throughout the world that don’t receive adequate sunlight also
prevent optimal levels of vitamin D.
Magnesium deficiency can lead to a drop in calcium levels, even when adequate
vitamin D and calcium are ingested.
In a three year study of men and women who were aged 65 or older it showed that
vitamin D and calcium supplementation led to a total body bone mineral density increase in
the second and third years of use. Over the
three year period there was a moderate decrease in bone loss and a reduced incidience of
non-vertebral fractures in all subjects.
Vitamin D maintains blood calcium levels by increasing dietary absorption of
calcium and reducing loss of calcium in urine.
Another study has shown that vitamin D deficiency can prevent normal bone
mineralisation, which leads to osteomalacia. In
osteomalacia, osteoclasts (bone eating cells) create tunnels and holes in bone, while
osteoblasts (bone forming cells) create a protein matrix that cannot be mineralized.
However, people with hyperparathyroidism should consult with a physician prior to
the use of vitamin D supplements.
Also an excessive intake of vitamin D may result in headaches, weight loss, kidney
stones, increased thirst, increased urination and diarrhea.
Nutritional Vitamin Supplements
o Maximol (liquid vitamins and
minerals)
o Orachel (multi-vitamin oral chelation
formula)
Other Nutritional Information
o Specific Vitamins and their benefits
o The role of Vitamins in our bodies
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